BIOLOGICAL STUDIES ON INDIVIDUAL BLEOMYCINS
نویسندگان
چکیده
منابع مشابه
Biosyntheses of new bleomycins.
Bleomycins, a group of glycopeptide antibiotics differ from one another in their terminal amine moieties. 14C-Methyl-labeled 3-aminopropyl-dimethylsulfonium was confirmed to be incorporated into the amine moiety of bleomycin A2. Addition of amines of bleomycin A2, A2'-a, A2'-b, A2'-c, A5, B2 and B4 to fermentation media increased the rate of production of the bleomycin which contained the added...
متن کاملRadioimmunoassay of bleomycins.
Rabbit antisera highly specific to the bleomycinic acid moiety of bleomycins were obtained by immunizing with a conjugate of copper-complex of bleomycin A5 and bovine serum albumin. These antisera not only reacted with bleomycin A5 but also with other bleomycins such as bleomycin A2, bleomycin B2 and peplomycin. The antisera showed little cross-reactivity with deamido-, depyruvamido- and decarb...
متن کاملStudies on Biological Oxidations
Pyruvic acid is one of the most reactive substances among those of importance in cellular metabolism. When carbohydrate is split during fermentation, pyruvic acid is the main end-product of the resulting series of phosphorylated oxidation-reductions. It thus becomes the immediate source for the formation of both lactic acid and alcohol. Pyruvic acid is decarboxylated by yeast; it may react with...
متن کاملStudies on Biological Oxidations
Introduction ........................................................ 691 Methods ............................................................ 693 Oxidation of carbohydrates by gonococci ............................ 694 “ “ hydroxy acids .......................................... 695 “ “ ketonic “ .......................................... 698 Organic acids and other substrates not oxidized by ...
متن کاملPhytochemical and biological studies on goniothalamus spp. in Borneo
Goniothalamus spp. are widely distributed is the island of Borneo. About 40 species of Goniothalamus have been recorded in Borneo. Goniothalamus spp. are widely used in traditional medicinal practices in Borneo especially in treating diarrhea, fever, skin diseases, antidotes and most commonly used as postparturation aids and as abortifacient. Some of the species are also being used as natural i...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: The Journal of Antibiotics
سال: 1968
ISSN: 0021-8820,1881-1469
DOI: 10.7164/antibiotics.21.592